Revealing the structure of clathrin-coated pits with DNA-PAINT

In this app note, we discuss how DNA-PAINT can be used to image cellular structures down to <20 nm resolution


The Nanoimager enables single-molecule imaging
at sub-20 nm resolution using a variety of SMLM
techniques, including DNA-PAINT.

Using this approach it is possible to: 

• Characterize the nano-architecture of
organelles and other cellular structures
• Reveal the spatial distributions of singlemolecules
• Assess protein co-localization
• Understand phenotypic changes in disease
• Visualize multiple markers by multiplexing
probes through microfluidics

Download our 'Revealing the structure of clathrin-coated pits with DNA-PAINT' app note here