In this app note, we discuss how super-resolution microscopy can be used to for simultaneous visualization of EV cargo and surface markers.
The Nanoimager enables
visualization and detection
of multiple surface markers
and internal protein cargo
simultaneously on individual EVs
with single-molecule sensitivity.
This type of research supports the:
• Using single-molecule sensitivity for better EV characterization
• Visualise single-EVs with 20 nm resolution and distinguish different biomarkers
• Detection of surface proteins alongside internal cargo proteins
• Quantify and measure the amount of cargo within a global population of EVs