Simultaneous visualization of EV cargo and
surface markers with single-molecule imaging

In this app note, we discuss how super-resolution microscopy can be used to for simultaneous visualization of EV cargo and surface markers.

SCR-20220907-m2u

 

The Nanoimager enables

visualization and detection

of multiple surface markers

and internal protein cargo

simultaneously on individual EVs

with single-molecule sensitivity.

This type of research supports the:

• Using single-molecule sensitivity for better EV characterization

• Visualise single-EVs with 20 nm resolution and distinguish different biomarkers

• Detection of surface proteins alongside internal cargo proteins

• Quantify and measure the amount of cargo within a global population of EVs

To discover more about how super-resolution microscopy can be used in EV research, visit our EV imaging series articles and EV hub.

Download our 'Simultaneous visualization of EV cargo and surface markers with single-molecule imaging' app note here